Diastereo‐ and Enantioselective Synthesis of a Novel Tetracyclic Ring System via an Organocatalytic One‐Pot Reaction

An efficient , asymmetric, one‐pot synthesis of a novel tetracyclic ring system incorporating both chroman and bicyclo[2.2.2]octane structural units was established through sequential reaction of nitroolefin enoates and α,β‐unsaturated ketones. Six stereogenic centers including two quaternary stereocenters were formed with excellent diastereo‐ and enantioselectivity.