Tetrahydroswertianolin (1), a new tetrahydroxanthone glycoside, was isolated from the whole plant of Swertia, MAKINO (Gentianaceae). Its structure was determined by chemical and spectroscopic methods including 2D-NMR. This compound was found to be very effective in immunologically induced liver injury in mice.
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Hase et al. (1997) studied this question.