Why the study?
Current ACS guidelines derive from trials in younger patients, leaving limited mid- and long-term data on medical therapy or interventions in octogenarians, where physicians often hesitate to apply standard guidelines due to complications.
Does an early invasive strategy improve survival in octogenarians with acute coronary syndrome compared to conservative management?
Does an early invasive strategy improve survival in octogenarians with acute coronary syndrome compared to conservative management?
Age alone should not be a contraindication for early invasive strategies in ACS, as PCI is associated with improved survival in octogenarians when accompanied by meticulous risk stratification.
Current guidelines for acute coronary syndrome are derived from the data in randomized clinical trials and metanalysis conducted in patients. These patients are generally of younger age. The data of acute coronary syndrome in octogenarians is mainly derived from registries. This mid and long-term data regarding medical therapy or interventions in octogenarians is low in number with smaller subsets of patients. Most of the physicians are reluctant to use the same guidelines in these elderly patients due to increased chances of complications. This article reviews the available data and literature in acute coronary syndrome in octogenarians and provides management perspectives for these elderly patients.
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Modi et al. (2020) conducted a review in Acute Coronary Syndrome. Early invasive strategy vs. Conservative strategy was evaluated.
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