Key result
Demented elderly women had significantly higher AT indices across all measured brain areas and significantly lower AC and ST indices in the P4 area compared to normal elderly women.
Why the study?
Does quantitative EEG analysis differentiate between normal and demented elderly women?
Cross-Sectional (n=33)
Yes
Does quantitative EEG analysis differentiate between normal and demented elderly women?
Quantitative EEG analysis reveals significant differences in brain activity indices between normal and demented elderly women, suggesting its potential utility as an objective tool for dementia diagnosis.
Answers are grounded in this paper and cite their sources.
qEEG may differentiate dementia in elderly women; hypothesis-generating and requires prospective validation before clinical adoption.
[Purpose] This study investigated the potential of quantitative electroencephalogram (EEG) analysis for dementia diagnosis by examining the correlation between each frequency band of EEG using a sample of normal and demented elderly women. [Subjects] Thirty-three elderly women (17 normal, 16 demented) without history of brain disease were participated in this study. [Methods] EEGs of the subjects were measured continuously for 5 minutes while subjects' eyes were closed. The AT index was defined as the ratio of the theta wave to the SMR wave; the AC index was defined as the ratio of the low beta wave to alpha wave; and the ST index was defined as the ratio of the high beta wave to the alpha wave. The differences in brain activity between normal and demented elderly women were analyzed using the Mann-Whitney test and the SPSSWIN (ver. 12.0) program. [Results] All areas showed a lower AT index among normal elderly women compared to demented elderly women. In the P4 area, the AC index and the ST index were significantly higher in normal than in demented elderly women, indicating there is a difference in brain activity between normal and demented elderly women. [Conclusion] These results show that quantitative EEG analysis can be used for dementia diagnosis.
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Ha et al. (2011) conducted a cross-sectional in Dementia (n=33). Dementia vs. Normal cognitive function was evaluated on Attention (AT) index in the P4 parietal lobe area (p=<0.05). Demented elderly women had significantly higher AT indices across all measured brain areas and significantly lower AC and ST indices in the P4 area compared to normal elderly women.
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