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A method for determination of the transfer of phosphate from creatine-phosphate to the hexosemonophosphates is described. It has been found that this transference is decreased in the muscle of rabbits fed tocopherol-deficient diets at a time when phosphoglucomutase activity and glycolysis are normal. The decrease in transference is not corrected by addition of ATP. ATP added at concentrations above 0.004 M inhibits phosphoglucomutase.
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Carpenter et al. (1958) studied this question.
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