Life Course Trajectories of Cardiovascular Risk Factors in Women With and Without Hypertensive Disorders in First Pregnancy: The HUNT Study in Norway

Figures

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  Figure 1. Flow chart of study population. HUNT indicates Nord‐Trøndelag Health Study.

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  Figure 2. Life course trajectories of mean systolic blood pressure (A), diastolic blood pressure (B), BMI (C), waist circumference (D), hip circumference (E), and waist‐to‐hip ratio (F) for women with normotensive and preeclamptic first pregnancies. Estimates are adjusted for age at measurement, HUNT survey, highest obtained education level, age at first birth, and ever daily smoking. Covariates are fixed at their means with gaps in the graphs corresponding to the woman's first pregnancy, birth at age 23 years, and a 3‐month postpartum period. BMI indicates body mass index; CI, confidence interval; HUNT, Nord‐Trøndelag Health Study.

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  Figure 3. Population average predicted probabilities of hypertension (defined as current antihypertensive medication and/or blood pressure ≥140 mm Hg systolic or ≥90 mm Hg diastolic) (A), obesity (defined as a BMI ≥30 kg/m2) (B), and diabetes mellitus (defined as self‐reported diabetes mellitus, nonfasting serum glucose ≥11.1 mmol/L, fasting serum glucose ≥7.0 mmol/L, and/or 2‐hour postload serum glucose ≥11.1 mmol/L) (C) by age in women with normotensive and preeclamptic first pregnancies. Estimates are adjusted for age at measurement, HUNT survey, highest obtained education level, age at first birth, and ever daily smoking. Covariates are fixed at their means with gaps in the graphs corresponding to the woman's first pregnancy, birth at age 23, and a 3‐month postpartum period. BMI indicates body mass index; CI, confidence interval; HUNT, Nord‐Trøndelag Health Study.

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  Figure 4. Life course trajectories of mean nonfasting serum non‐HDL (A) and HDL (B) cholesterol, triglycerides (C), and glucose (D), resting heart rate (E), and serum CRP (F) for women with normotensive and preeclamptic first pregnancies. Estimates are adjusted for age at measurement, HUNT survey highest obtained education level, age at first birth and ever daily smoking. Analyses of glucose and triglycerides were additionally adjusted for time since last meal. Covariates are fixed at their means with gaps in the graphs corresponding to the woman's first pregnancy, birth at age 23, and a 3‐month postpartum period. CRP is given as geometric mean. CI indicates confidence interval; CRP, C‐reactive protein; HDL, high‐density lipoprotein; HUNT, Nord‐Trøndelag Health Study.