Key result
In pregnant women with rheumatic heart disease, maternal mortality was 4%, while fetal complications included a 46% rate of low birth weight and an 18% rate of preterm delivery.
Why the study?
Rheumatic heart disease remains a global health burden, and pregnancy increases cardiac demand and associated risks, potentially leading to adverse fetomaternal outcomes.
Observational (n=50)
No
Rheumatic heart disease during pregnancy is associated with significant maternal and fetal morbidity, including a 4% maternal mortality rate and a 46% rate of low birth weight neonates.
High RHD pregnancy risks support specialized care; leaves open optimal strategies pending larger prospective data.
Background: Rheumatic heart disease (RHD) remains a significant global health burden, particularly among pregnant women in regions with limited access to healthcare. Pregnancy exacerbates the risks associated with RHD due to increased cardiac demand, potentially leading to adverse fetomaternal outcomes. This study aims to investigate the fetomaternal outcomes associated with RHD during pregnancy. Specific objectives include assessing the maternal outcome of patients with rheumatic heart disease in pregnancy and investigating the fetal outcome. Methods: It was a retrospective observational study to assess the outcomes of pregnant women and neonatal outcomes. Results: The findings reveal a significant burden of adverse fetomaternal outcomes associated with RHD during pregnancy. Maternal complications, such as maternal mortality (4%), mean gestational age 39.17 years, valvular disorder and mode of delivery, and fetal complications, including preterm birth, low birth weight, intrauterine growth restriction, and neonatal mortality, were also elevated in this population. Conclusions: Moving forward, further research is essential to enhance our understanding and optimize care for pregnant women with RHD.
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Prasad et al. (2025) conducted an observational in Rheumatic heart disease in pregnancy (n=50). Rheumatic heart disease was evaluated on Fetomaternal outcomes (maternal mortality, mode of delivery, fetal birth weight, neonatal mortality). In pregnant women with rheumatic heart disease, maternal mortality was 4%, while fetal complications included a 46% rate of low birth weight and an 18% rate of preterm delivery.
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