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Phenylketonuria is a disease characterized by gross mental deficiency and by the excretion of phenylpyruvic acid in the urine.It is recessively inherited, affects both sexes equally, and appears to occur only in man, no equivalent error of metabolism having, as yet, been found in any other animal species.Within the last 10 years it has been found that, if a diet poor in phenylalanine is given from soon after birth, the mental deficiency can be avoided and affected children develop normally.Several reviews on phenylketonuria have appeared recently (Jervis, 1954;Lang, 1955 ; Knox, 1 9 6 0 ~) .
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L. I. Woolf (1962) studied this question.
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