Literature review reveals the genotoxic and mutagenic risks of aluminum, iron, and manganese in human cells, highlighting their potential role in rising neurodegenerative disorders.
There is considerable evidence indicating an increase in neurodegenerative disorders in industrialized countries. The clinical symptoms and the possible mutagenic effects produced by acute poisoning and by chronic exposure to metals are of major interest. This study is a review of the data found concerning the genotoxic potential of three metals: aluminum (Al), iron (Fe) and manganese (Mn), with emphasis on their action on human cells.
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Lima et al. (2011) studied this question.
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