Key result
A fast-track recovery protocol for major liver resection reduced postoperative morbidity (25% vs 60%, p=0.002) and length of stay (5.75 vs 13.5 days, p<0.001) compared to conventional care.
Why the study?
Does a fast-track recovery protocol reduce perioperative morbidity, length of hospitalization, and readmission rate in patients undergoing major liver resection for malignant tumors?
RCT (n=62)
randomized
Does a fast-track recovery protocol reduce perioperative morbidity, length of hospitalization, and readmission rate in patients undergoing major liver resection for malignant tumors?
Absolute Event Rate: 25% vs 60%
p-value: p=0.002
A fast-track recovery protocol significantly reduces postoperative complications and length of hospital stay in patients undergoing major liver resection for malignant tumors.
Supports fast-track protocols after major liver resection; extends enhanced recovery evidence to hepatobiliary oncology.
The objective of this study was to compare fast-track (FT) recovery protocol with the conventional one in patients treated with major liver resection by evaluating perioperative morbidity, length of hospitalization, and readmission rate. Sixty-two patients suffering from malignant liver tumors were surgically treated from May 2012 to April 2014. After randomization, they were prospectively divided into two groups: Group A patients (n = 32) followed FT recovery protocol and Group B patients (n = 30) were treated with the conventional (CON) protocol. Postoperative morbidity, readmission rate, and median hospital stay in the two groups were studied. Fast-track protocol was associated with a decreased complication (25%, p = .002), whereas the risk of postoperative morbidity was 2.4 times higher in patients treated with the CON protocol (60%, p = .002). Readmission rate was not significantly different between the two groups (6.25%, p = .35). Age (p = .382) and body mass index (p = .818) were not a suspending factor for following the FT protocol. Overall length of stay (postoperative days) in the FT group was (mean ± SD) 5.75 ± .5 and in the CON group was 13.5 ± 6.7 (p < .001). Fast-track recovery protocol seems to be safe and particularly efficient in patients undergoing major liver resections.
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Καπρίτσου et al. (2018) conducted an RCT in Malignant liver tumors (n=62). Fast-track recovery protocol vs. Conventional protocol was evaluated on Postoperative morbidity (p=0.002). A fast-track recovery protocol for major liver resection reduced postoperative morbidity (25% vs 60%, p=0.002) and length of stay (5.75 vs 13.5 days, p<0.001) compared to conventional care.
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