Key result
Primary composite cardiovascular endpoints occurred in 50 of 528 patients (9.5%), with these patients exhibiting more pronounced seasonal blood pressure variability, particularly inverted nocturnal BP.
Cohort (n=770)
Yes
Significant seasonal fluctuations in blood pressure, particularly an 'inverted' pattern where summer nocturnal BP exceeds winter BP, are associated with adverse cardiovascular outcomes in hypertensive patients.
Seasonal BP variability was associated with higher CV events in hypertension; hypothesis-generating, prospective trials needed before practice change.
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Горбунов et al. (2020) conducted a cohort in Arterial hypertension (n=770). Seasonal variability of blood pressure was evaluated on Composite of death, myocardial infarction, stroke, development of heart failure, and other cardiovascular complications. Primary composite cardiovascular endpoints occurred in 50 of 528 patients (9.5%), with these patients exhibiting more pronounced seasonal blood pressure variability, particularly inverted nocturnal BP.
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