Polymorphonuclear leukocyte chemotaxis in the absence of oxygen

Human polymorphonuclear leukocytes were tested for chemotactic migration in the Boyden Chamber system. The attracting agent was activated human plasma. Experiments were carried out in a strictly anaerobic environment in which all the suspensions assumed a very low redox potential. Control experiments were carried out in an aerobic environment. Chemotactic migration occurred equally well under both conditions.