Answers are grounded in this paper and cite their sources.
Silver-catalyzed C(sp(2))-H functionalization/C-O cyclization has been developed. The scalable reaction proceeds at room temperature in an open flask. The present method exhibits good functional-group compatibility because of the mild reaction conditions. Using a AgNO3 catalyst and a (NH4)2S2O8 oxidant in CH2Cl2/H2O solvent, various lactones are obtained in good to excellent yields. A kinetic isotope effect (KIE) study indicates that the reaction may occur via a radical process.
No takes yet. Share an insight, caveat, or question.
Dai et al. (2014) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: