A battery of tests has been used to measure the effects of several drugs upon skills used in driving an automobile and in some other related activities. The tests included a driver trainer test, a steadiness test, and visual tests, and they were applied to both normal subjects and patients. The effects of various dosages of drugs were determined; the list included meprobamate, dextro amphetamine sulfate, prochlorperazine, benactyzine HCl, chlordiazepoxide, isothipendyl HCl, syrosingopine, and others. It is suggested that objective tests of the kind used here be used regularly in evaluating new compounds that can affect the central nervous system.
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James G. Miller (1962) studied this question.