Application of Crystallization Inhibitors to Chiral Separations. 2. Enhancing the Chiral Purity of Mandelic Acid by Crystallization

In part 1 of this work, the successful design of additives for the selective inhibition of ( R, S ) - mandelic acid crystallization was described. Now, in part 2 of our study, we show how such additives may be used, together with the known ternary phase diagram, as the basis for a crystallization process that yields a chirally enriched product.