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September 17, 2010Biochemistry

Thermodynamic Stability and Folding Kinetics of the Major G-Quadruplex and Its Loop Isomers Formed in the Nuclease Hypersensitive Element in the Human c-Myc Promoter: Effect of Loops and Flanking Segments on the Stability of Parallel-Stranded Intramolecular G-Quadruplexes

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Authors

EHEmmanuel HatzakisThe Ohio State UniversityKOKeika OkamotoUniversity of ArizonaDYDanzhou YangPurdue University West Lafayette

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Hatzakis et al. (2010) studied this question.

synapsesocial.com/papers/6a9cab04c42eb00825f7bf06https://doi.org/10.1021/bi100946g
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism1999 · 1,745 citations
  2. 2An Intramolecular G-Quadruplex Structure with Mixed Parallel/Antiparallel G-Strands Formed in the Human BCL-2 Promoter Region in Solution2006 · 405 citations