Functional endothelin and angiotensin receptors have been expressed in Xenopus oocyte following the microinjection of rat heart mRNA. Under voltage clamp conditions, application of these peptides clearly induced oscillatory Ca2+-activated chloride currents in a dose-dependent manner. In addition, no direct modulation of expressed or native cardiac Ca channels was observed.
No takes yet. Share an insight, caveat, or question.
Lory et al. (1989) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: