Key result
Surgical excision of biatrial myxomas in a 35-year-old man with Carney complex resulted in successful tumor removal with no recurrence at one year follow-up.
Case Report (n=1)
Biatrial cardiac myxomas, especially when associated with endocrine abnormalities, should raise high clinical suspicion for Carney complex and prompt genetic testing.
Supports feasibility of biatrial myxoma excision in Carney complex; hypothesis-generating for surveillance and genetic screening protocols.
Cardiac myxomas make up approximately 50% of all benign cardiac tumors and represented 86% of all surgically treated cardiac tumors. Most of them originated from the left atrium, in some cases from both of atria. We report a case of male patient with biatrial myxomas and other extra-cardiac involvement: hypophyseal adenoma, enlargement of thyroid gland, tubular adenoma polyp of colon and bilateral large cell calcifying Sertoli cell tumor (LCCSCT) of testis. These findings led to the diagnosis of Carney's complex, which is a syndrome with multiple neoplasias, cardiac myxomas, lentigines, and endocrine abnormalities. A genetic test confirm this diagnosis.
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Havránková et al. (2013) conducted a case report in Carney Complex with Biatrial Cardiac Myxoma (n=1). Surgical excision was evaluated on Tumor recurrence. Surgical excision of biatrial myxomas in a 35-year-old man with Carney complex resulted in successful tumor removal with no recurrence at one year follow-up.
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