Nortopsentin D, an antifungal 2,4-diinodolylimidazole, is synthesized by use of a successive and regioselective diarylation, in which N-protected 2,4,5-tri- and 4,5-di-bromoimidazole derivatives are treated with N-silylated 3-indolylboric acid in the presence of a palladium(o) catalyst.
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Kaswasaki et al. (1994) studied this question.
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