Key result
The Mannheim Peritonitis Index (MPI) score accurately predicted 7-day mortality in patients with peritonitis, demonstrating a sensitivity of 91.8%, specificity of 84.4%, and diagnostic accuracy of 93%.
Why the study?
Diagnosis and prognosis of acute intraperitoneal infection remain challenging, prompting evaluation of the Mannheim Peritonitis Index for predicting mortality.
Does the Mannheim Peritonitis Index (MPI) accurately predict mortality in patients with peritonitis?
Cross-Sectional (n=200)
No
Does the Mannheim Peritonitis Index (MPI) accurately predict mortality in patients with peritonitis?
Effect estimate: Sensitivity 91.8%, Specificity 84.4%, Diagnostic Accuracy 93.0%
The Mannheim Peritonitis Index is a highly sensitive and specific tool for predicting 7-day mortality in patients with acute intraperitoneal infection.
MPI may aid early mortality risk stratification in peritonitis; leaves open prospective validation before practice change.
Introduction: Despite latest development the diagnosis and prognosis of acute intraperitoneal infection is still offer a challenge. Different scoring algorithms have been formulated to grade the severity and decision making.Objective: To document reliability of Mannheim Peritonitis Index as a criterion for prediction of mortality after acute intraperitoneal infectionMethodology: This cross-sectional study was conducted at department of Surgery; Civil Hospital Karachi/Dow University of Health Sciences during December 2019 to June 2020. Total 200 patients aged 16 to 55 years from either gender, presenting with peritonitis were enrolled. Patients were evaluated using Mannheim Peritonitis Index (MPI) score for mortality taking real mortality within 7 days as gold standard.Results: The mean age was 37.3 ±9 years with male (71%) dominance, while mean MPI score was 27.12 ±7.1. The sensitivity was 91.8 %, specificity was 84.4 %, while positive predictive and negative predictive values and diagnostic accuracy values were 87.8 %, 89.4 % and 93% respectively.Conclusion: Several scoring systems are utilized to evaluate and stratify patients in overcrowded emergency department which is crucially important for selection of patients who need early clinical decisions. MPI scoring index is the specific and simply accessible in such condition to predict the mortality.
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Rizvi et al. (2023) conducted a cross-sectional in Peritonitis after hollow organ perforation (n=200). Mannheim Peritonitis Index (MPI) score vs. Actual mortality within 7 days (gold standard) was evaluated on Prediction of mortality within 7 days (Sensitivity 91.8%, Specificity 84.4%, Diagnostic Accuracy 93.0%). The Mannheim Peritonitis Index (MPI) score accurately predicted 7-day mortality in patients with peritonitis, demonstrating a sensitivity of 91.8%, specificity of 84.4%, and diagnostic accuracy of 93%.
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