Memorin is an ayurvedic remedy for improving mental function. Standardization of Ayurvedic formulations is an important step for the establishment of a consistent biological activity, a consistent chemical profile, or simply a quality assurance program for production and manufacturing of herbal drugs. WHO specific guidelines for the assessment of the safety, efficacy and quality of herbal medicines as a prerequisite for global harmonization are of importance. The aim of present study is Quality standardization and toxicity study of Memorin. Standardization of drug was done on the basis of evaluating the drug for its Physico-chemical parameters and presence of phytochemical constituents. It includes total ash value, extractive values, loss on drying, bulk density, tapped density etc. Drug was evaluated for presence of alkaloids, proteins, steroids, tannins, glycosides etc. Qualitative evaluation of the drug was performed by means of FT-IR, GC-MS and HPLC. In HPLC, C18 column was used. Flow rate was 1 ml/min. Mobile phase for HPLC analysis was methanol: ammonium acetate and it was run at 350nm for detection of compounds. Toxicity study of drug was done by using animals (Wistar albino rats). It can be concluding that the drug was safe and there was no sign of toxicity and mortality.
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Smita et al. (2014) studied this question.