Sulfanilamide in the Treatment of Chancroid

Since sulfanilamide was first found to be of value in hemolytic streptococcic infections, the question of ascertaining its action in infections caused by the hemophilic streptobacillus of Ducrey suggested itself. Previous to the present writing, reports on this subject, all of which have been encouraging, have come from three British clinics1and from one American group.2Since we have available a large hospitalized venereal service, it is felt that our experiences are worthy of record. Sulfanilamide has been used in the treatment of chancroid at the Cleveland City Hospital since July 1937. This report covers a series of thirty-seven cases, which were very carefully selected and were considered suitable for this study. For comparison there is also presented, as a control group, a series of sixty similar cases, most of which were seen before July 1937, and which were treated by other methods. CRITERIA FOR SELECTION OF CASES