Key result
Cardiac ruptures from myocardial infarction and aortic dissection produced significantly greater pericardial effusion volumes with blood clots compared to cardiopulmonary resuscitation and blunt trauma (P<0.05).
Why the study?
To analyze the morphological features and forensic pathological characteristics of cardiac ruptures of different causes for their differential diagnosis.
Observational (n=44)
No
p-value: p=<0.05
Hemorrhage, inflammatory cell infiltration, and lateral thrombi around cardiac ruptures are key forensic indicators of antemortem injury.
Supports forensic diagnosis of antemortem cardiac rupture via histology; leaves open validation in larger series.
OBJECTIVE: To analyze the morphological features and forensic pathological characteristics of cardiac ruptures of different causes for their differential diagnosis. METHODS: We analyzed the data of 44 autopsy cases of cardiac rupture from 2014 to 2017 in our institute, including 11 cases caused by blunt violence with intact pericardium, 4 caused by cardiopulmonary resuscitation (CPR), 9 by myocardial infarction, and 20 by aorta dissection rupture.The gross features and histopathological characteristics of cardiac rupture and pericardial effusion were analyzed and compared. CONCLUSIONS: Hemorrhage, inflammatory cell infiltration, and lateral thrombi around the cardiac rupture, along with pericardial blood clots, are all evidences of antemortem injuries.
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Wang et al. (2018) conducted an observational in Cardiac rupture (n=44). Causes of cardiac rupture (blunt trauma, myocardial infarction, CPR, aortic dissection) vs. Cross-comparison between causes was evaluated on Pericardial effusion volume and histopathological features (p=<0.05). Cardiac ruptures from myocardial infarction and aortic dissection produced significantly greater pericardial effusion volumes with blood clots compared to cardiopulmonary resuscitation and blunt trauma (P<0.05).
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