An unusually substantial coupling is observed across the hydrogen bond of fully 15N-labeled compound 1 when it is studied by 1H and 15N NMR spectroscopy. The structure was determined by X-ray diffraction and shown to correspond to tautomer 1 a (both in the solid state and in solution). These results open up a new field of hydrogen-bond research by NMR spectroscopic methods.
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Claramunt et al. (2001) studied this question.
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