A multiscale architecture with interlaced submicrometer ridges and nanoprotrusions is built on a polydimethylsiloxane (PDMS) surface by a combination of self-assembly, soft lithography, and physical treatment (see picture). The multiscale structure reduces activated-platelet adhesion under flow conditions, which is significant for the development of blood-contacting materials.
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Fan et al. (2009) studied this question.
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