Platelet aggregation induced by ADP in canine platelet-rich plasma was inhibited by volatile anesthetics. The partial pressures at which platelet aggregation was inhibited 50 per cent correlated closely with the pressures used clinically: methoxyflurane, 3.5 torr; halothane, 7.5 torr; diethyl ether,
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Issaku Ueda (1971) studied this question.
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