The excellent biocompatibility of calcium phosphate (CaP) coatings makes them widely used in magnesium (Mg) alloy orthopedic implant materials. However, the porous morphology of CaP coatings limits their corrosion resistance. A cupric oxide (CuO) doped titania (TiO 2 ) sol–gel coating is prepared on a porous hydroxyapatite (HA) coating. According to electrochemical test results, the HA/CuO–TiO 2 coating obtains a current density of 6 × 10 –4 mA/cm 2, lower than that of the Mg alloy (2.6 × 10 –2 mA/cm 2 ). The hydrogen evaluation of the HA/CuO–TiO 2 coating is only 1/12 that of the Mg alloy after immersion for 7 days. In addition, the HA/CuO–TiO 2 coating has an antibacterial rate of 99.5 ± 0.4% against Staphylococcus aureus, significantly higher than that of the HA coating (19.8 ± 0.3%) and HTC0 coating (38.4 ± 0.5%). The CuO doped composite coating has no adverse effect or cytotoxicity on cell proliferation (cell viability ≥79.6%). Hence, the HA/CuO–TiO 2 composite coating is useful for enhancing the corrosion resistance and antibacterial properties of Mg alloys while ensuring cytocompatibility. The HA/CuO–TiO 2 coated AZ60 Mg alloy can meet the requirements of clinical application.
No takes yet. Share an insight, caveat, or question.
Xu et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: