What question did this study set out to answer?

To assess how maternal magnesium sulphate treatment affects mineral status and parathyroid hormone secretion in preterm infants during the first two weeks of life.

March 1, 2001Acta Paediatrica

Antenatal magnesium sulphate exposure is associated with prolonged parathyroid hormone suppression in preterm neonates

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To assess how maternal magnesium sulphate treatment affects mineral status and parathyroid hormone secretion in preterm infants during the first two weeks of life.
Monitored mineral concentrations and parathyroid hormone secretory response in 8 magnesium sulphate-exposed and 27 control preterm neonates over the first 2 weeks of life.
Antenatal magnesium sulphate exposure caused hypermagnesaemia lasting 3 to 7 days after birth without altering other serum mineral concentrations.
Early hypermagnesaemia was associated with hypercalciuria during the first 3 days of life and prolonged parathyroid hormone suppression lasting up to 2 weeks of age.

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Implication

Comparative study reveals prolonged parathyroid hormone suppression in preterm neonates exposed to antenatal magnesium sulphate, indicating altered neonatal mineral regulation.

Cite This Study

Rantonen et al. (2001) studied this question.

synapsesocial.com/papers/6a9cdd0660ceabfff382d092 https://doi.org/10.1111/j.1651-2227.2001.tb00304.x

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Implication

Comparative study reveals prolonged parathyroid hormone suppression in preterm neonates exposed to antenatal magnesium sulphate, indicating altered neonatal mineral regulation.

Antenatal magnesium sulphate exposure is associated with prolonged parathyroid hormone suppression in preterm neonates

Key Points

Discussion

Implication

Cite This Study

Antenatal magnesium sulphate exposure is associated with prolonged parathyroid hormone suppression in preterm neonates

Key Points

Discussion

Implication

Cite This Study

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