Unveiling Reliable Catalysts for the Asymmetric Nitroaldol (Henry) Reaction

This is the authors' abstract. We don't add key points for this paper.

Conceptually different chiral catalysts ranging from polymetallic complexes to Lewis acids and organocatalysts have emerged for solving the long-standing problem of stereocontrol in the Henry reaction, a fundamental CC bond-forming process (see scheme). New catalyst systems with improved selectivity have increased the synthetic value of this reaction considerably.