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OBJECTIVE: Phenolic compounds have been considered inhibitors of various cancers. MATERIAL AND METHODS: gene expression were studied by real-time RT-PCR. Also, protein network and different interactions between the desired genes were analyzed using GeneMANIA database. RESULTS: gene expression; this alteration in gene expression probably occurred along with the activation of intrinsic apoptotic signaling pathway. CONCLUSION: Via apoptosis induction, caffeic acid and gallic acid have induce toxic effects and morphological changes in breast cancer cells, suggesting their possible future application as antitumor agents.
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Rezaei-Seresht et al. (2019) studied this question.