Ergosterol-5, 8-peroxide (I) was isolated from a variation of Cercospora kikuchii obtained by irradiation with light. It showed potent cytotoxicity (IC50=3.5 μg/ml) against mouse lymphemia L-1210/v/c in vitro, but exhibited no significant antitumor activity against both leukemia P-388 in CDF1 mouse and sarcoma 180 in dd mouse. Peroxide I also did not affect on both gram-positive and gram-negative bacteria.
No takes yet. Share an insight, caveat, or question.
MATSUEDA et al. (1982) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: