Trichloroacetimidates, generated either in situ or prepared and isolated from methyl 3‐hydroxycycloalk‐1‐enecarboxylates, undergo stereoselective intramolecular conjugate addition reactions to produce oxazolines. These oxazolines lead, in a novel, simple way, to 2‐amino‐3‐hydroxycycloalkanecarboxylic acids and their derivatives. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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Matsushima et al. (2009) studied this question.
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