Key result
The presence of three or more cardinal symptoms of angina is associated with a significantly higher probability of STEMI compared to fewer symptoms (p=0.001).
Why the study?
Does the number of patient-reported angina symptoms correlate with the diagnosis of STEMI?
Observational (n=230)
No
Does the number of patient-reported angina symptoms correlate with the diagnosis of STEMI?
p-value: p=0.001
An increasing number of patient-reported cardinal angina symptoms (retrosternal chest discomfort, diaphoresis, palpitations, radiation) directly correlates with a higher probability of STEMI.
Symptom count may aid STEMI probability assessment; hypothesis-generating and requires prospective validation before changing triage.
Introduction: Chest pain is amongst the commonest causes of visits to the emergency department. A rapid assessment with a prompt evaluation with an electrocardiogram clinches the diagnosis in most cases. However, with ever increasing strain on our limited resources, patient reported symptoms are central to initial assessment and must decide the course of action. Although considered ominous signs requiring further, often emergent, assessment, data on correlation of symptoms of angina with ST segment elevation is limited in contemporary literature. Methodology: 230 patients with biomarker proven ST segment elevation myocardial infarction (STEMI) were studied and assessed for frequency of the four, patient reported, cardinal symptoms of angina, namely retrosternal chest discomfort, diaphoresis, palpitations and radiation. We assessed the relative presence or absence of these supposedly cardinal symptoms of angina and set out to classify the most important symptoms of angina. Results: Our study shows that presence of three or more above symptoms is associated with a much higher possibility of an actual STEMI as opposed to only one symptom. Furthermore, a measurable increase in the probability of MI exists, when the number of patient reported symptoms increases from none to all four, as mentioned above. Though the study also reaffirmed the association between hypertension and Type 2 Diabetes Mellitus with acute coronary syndromes, our study was neither powered, nor designed to study this association. Conclusions: Patient reported symptoms have a direct and additive correlation with STEMI. A quick but detailed history in the emergency department is of paramount importance to identify high risk patients.
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Mujeeb et al. (2017) conducted an observational in ST Segment Elevation Myocardial Infarction (STEMI) (n=230). Cardinal symptoms of angina (retrosternal chest discomfort, diaphoresis, palpitations, radiation) vs. Fewer or no symptoms was evaluated on Occurrence of STEMI based on the number of anginal symptoms present (p=0.001). The presence of three or more cardinal symptoms of angina is associated with a significantly higher probability of STEMI compared to fewer symptoms (p=0.001).
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