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A 10-year-old boy had pain in the right thigh that interfered with activities, awoke him at night, and was only slightly relieved by acetaminophen. Magnetic resonance imaging and radionuclide bone scans showed a large area of abnormality within the femur. Computed tomography–guided (CT) biopsy was not completed because of the patient's agitation, but CT images showed a small lytic lesion in the cortex surrounded by dense bone. A diagnostic and therapeutic procedure was performed.
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Gebhardt et al. (2005) studied this question.
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