Answers are grounded in this paper and cite their sources.
A princely synthesis: The hypothetical key step in the biosynthesis of the decahydroquinoline dendrobatid alkaloids, such as cis-195 A found in frogs, from 1,5-polycarbonyl derivatives is mimicked by using (R)-phenylglycinol as a chiral latent form of ammonia in a double cyclocondensation reaction.
No takes yet. Share an insight, caveat, or question.
Amat et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: