Carbon Nanotube Paper‐based Electrode for Electrochemical Detection of Chemicals in Rat Microdialysate

Paper‐based analytical devices, which are suited to point‐of‐care diagnostics and on‐site detection because of cheap price and portability, have attracted increasing attention for improving global health and in other applications. Here, we constructed one carbon nanotube paper‐based electrode (CNTPE) for the detection of neurochemicals in brain microdialysate. CNTPE was directly fabricated through filter depositing CNT dispersion onto the surface of filter paper. The fabricated CNTPE have good electrochemical performance with advantage of CNT, which not only facilitate ascorbic acid (AA) oxidation, also could as a good platform to functionalize. As a proof, we demonstrate that the CNTPE act as electrode to detect AA directly and detect glucose with further modified CNTPE through electrodeposited Prussian blue (PB). The results show that the easily prepared CNTPE can be used for the selective measurement of AA without interference from dopamine and other electrochemical active substances; what's more, PB and glucose oxidase (GOx) modified CNTPE has good performance towards the specific detection of glucose. Therefore, we believe that CNTPE would have great potential application in detection of chemicals to understand the function of brain.