Key result
A troponin I-like factor purified from pig platelets participated in the in vitro reconstitution of a thin filament-like complex with 55% calcium sensitivity.
A troponin I-like factor purified from pig platelets can participate in a calcium-sensitive thin filament-like complex in vitro.
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No immediate clinical implications; leaves open a platelet-derived role in calcium-sensitive filament regulation pending in vivo studies.
Terrossian et al. (1983) studied this question. Purification of a troponin I-like factor was evaluated on Reconstitution in vitro of a thin filament-like complex modulating platelet actin-activated Mg2+-dependent ATPase activity. A troponin I-like factor purified from pig platelets participated in the in vitro reconstitution of a thin filament-like complex with 55% calcium sensitivity.
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