Prospective clinical trial demonstrates high aesthetic satisfaction and improved self-image in adults receiving mandibular filler, highlighting positive patient-reported outcomes.
Background/Objectives: Mandibular angle volumization with hyaluronic acid is used to redefine facial contours and improve the aesthetics of the lower third of the face. However, beyond the aesthetic outcomes, it is important to understand the impact of this intervention on the aesthetic perception of subjects undergoing the procedure. This preliminary prospective, non-randomized, uncontrolled clinical trial aimed to evaluate post-treatment aesthetic satisfaction and facial appearance perception in subjects who underwent mandibular angle volumization with hyaluronic acid. Methods: Ten adults (eight women and two men) with a mean age of 34.30 ± 11.20 years participated in the study. Subjects underwent injection of 2 mL of hyaluronic acid per hemiface, following the Medical Codes protocol. Volumetric analysis of the mandibular angle region was performed using the Vectra 3D imaging system. Aesthetic perception and facial self-image were assessed 60 days after the procedure using the Orofacial Esthetic Scale and FACE-Q questionnaires. Results: Volumetric analysis demonstrated descriptively higher values throughout the clinical follow-up on both sides, although no statistically significant differences were observed (p > 0.05). The questionnaires revealed high levels of aesthetic satisfaction and positive perception of facial appearance. On the Orofacial Esthetic Scale, a predominance of high aesthetic satisfaction was observed among subjects. Likewise, FACE-Q results demonstrated high levels of satisfaction related to facial appearance and self-image. Conclusions: Within the limitations of this preliminary secondary analysis, mandibular angle volumization with hyaluronic acid was associated with high post-treatment aesthetic satisfaction and favorable facial appearance perception at the 60-day follow-up. These findings are descriptive and warrant confirmation in larger controlled studies.
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Bettiol et al. (2026) studied this question.
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