Key result
18 F-FDG PET/CT reveals hypermetabolic masses and peritoneal thickening to diagnose desmoplastic small round cell tumor.
Case Report (n=1)
DSRCT should be considered in young men presenting with extensive peritoneal involvement on imaging, and molecular confirmation is essential for accurate diagnosis.
Answers are grounded in this paper and cite their sources.
May prompt DSRCT consideration in young men with peritoneal FDG-avid masses; leaves open prospective validation of imaging criteria.
A 21-year-old man presented with 1-month intermittent abdominal pain and distension. Contrast-enhanced CT and 18 F-FDG PET/CT demonstrated diffuse peritoneal thickening and multiple hypermetabolic masses, initially raising suspicion for malignant disease. Biopsy showed nests of small round blue cells within a desmoplastic stroma. Fluorescence in situ hybridization (FISH) confirmed EWSR1‑WT1 gene fusion, establishing the diagnosis of desmoplastic small round cell tumor (DSRCT). This case highlights that DSRCT should be considered in young men with extensive peritoneal involvement, and that molecular confirmation is essential to avoid diagnostic delay.
No takes yet. Share an insight, caveat, or question.
Feng et al. (2026) conducted a case report in Desmoplastic small round cell tumor (DSRCT) (n=1). 18 F-FDG PET/CT was evaluated. 18 F-FDG PET/CT demonstrated diffuse peritoneal thickening and multiple hypermetabolic masses in a 21-year-old man, leading to a diagnosis of desmoplastic small round cell tumor confirmed by FISH.
Synapse has enriched 10 related papers. Consider them for comparative context: