Key result
Minimally invasive mitral valve repair via mini right thoracotomy achieved an equivalent successful repair rate of 84% compared to conventional median sternotomy in patients with rheumatic heart disease.
Why the study?
Does mini right thoracotomy provide equivalent clinical and echocardiographic outcomes compared to conventional sternotomy for mitral valve repair in patients with rheumatic heart disease?
RCT (n=50)
Prospective simple randomization
No
Does mini right thoracotomy provide equivalent clinical and echocardiographic outcomes compared to conventional sternotomy for mitral valve repair in patients with rheumatic heart disease?
Mini right thoracotomy is a feasible and safe alternative to median sternotomy for mitral valve repair in rheumatic heart disease, offering equivalent repair rates and functional outcomes.
Answers are grounded in this paper and cite their sources.
Equivalent outcomes support mini right thoracotomy as alternative to sternotomy; extends RCT evidence to rheumatic mitral disease.
Purpose: Right mini thoracotomy has been evaluated in many studies for mitral valve repair mainly in degenerative valvular disease but not in rheumatic heart disease. Mitral valve repair is more challenging in rheumatic etiology due to complexity of lesions. This prospective randomized case control study was designed to evaluate repair through mini right thoracotomy and to compare the clinical and echocardiographic outcomes with sternotomy in rheumatic patients. Methods: 25 patients of rheumatic heart disease underwent mitral valve repair through mini right thoracotomy (group I). Various clinical and functional parameters were compared with 25 patients of mitral valve repair through sternotomy (group II). On follow up the results were compared in both groups for clinical and echocardiographic parameters. Results: The various pre-operative demographic parameters were comparable in two groups. Equal rate of mitral valve repair (group I-21/25, 84% and group II-21/25, 84%) was achieved in both groups. The various intra-operative and post-operative clinical parameters were better in group I .There were equivalent functional and valve related outcomes in both groups in term of NYHA class (1.28 ± 0.613 vs 1.08 ± 0.276, P = 0.144), post-operative mitral valve area (2.43 ± 0.891 vs 2.82 ± 0.662, P = 0.090), incidence of more than mild mitral regurgitation (0) and mean pressure gradient across mitral valve (4.98 ± 3.33 vs 4.23 ± 1.5, P = 0.309). Conclusion: Mitral valve repair through mini right thoracotomy approach in rheumatic etiology is feasible and safe with equivalent rate of successful repair as compared to median sternotomy. It is associated with lesser morbidity, cosmetic advantage and lesser resource utilization.
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Chahal et al. (2016) conducted an RCT in Rheumatic mitral valve disease (n=50). Minimally invasive mitral valve repair via mini right thoracotomy vs. Conventional mitral valve repair via median sternotomy was evaluated on Successful mitral valve repair rate (p=1.0). Minimally invasive mitral valve repair via mini right thoracotomy achieved an equivalent successful repair rate of 84% compared to conventional median sternotomy in patients with rheumatic heart disease.
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