“Click” to fold: CuI-catalyzed azide–alkyne cycloaddition polymerization of a peptide monomer induced folding of the resultant polymer into well-defined β sheets, which further self-assemble into hierarchical nanofibrils. The antiparallel β-sheet structure was confirmed by several techniques. Scanning probe micrographs confirm the formation of hierarchical amyloid-like nanofibrils.
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Yu et al. (2008) studied this question.
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