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We report the unique thermoresponsive properties of fluorinated polyacrylamides, poly[N-(2,2-difluoroethyl)acrylamide] (P2F). The solubility of fluorinated polyacrylamides in water can be easily controlled by changing the number of fluorine atoms in N-ethyl groups. Moreover, we demonstrate that fluorinated polyacrylamides are less cytotoxic than poly(N-isopropylacrylamide) (PNIPAM).
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Bak et al. (2012) studied this question.
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