Why the study?
Existing methods for estimating components in multicomponent formulations typically require separation of active components, which is tedious, time-consuming, and lacks accuracy.
The study developed an HPTLC method for the simultaneous estimation of aspirin and clopidogrel in combined formulations to overcome the tediousness of separating active components.
No clinical data presented; leaves open any implications for aspirin-clopidogrel formulation analysis or use.
Now a days multicomponent formulations are becoming more popular in order to ensure timely and complete medication in multidrug therapy and enhancement of patient compliance. Through, analytical methods for single drug are extensively available, still due to complexity in multicomponent formulation, method development for the individual active component is sort of challenge for the analytical chemist. Information in the books also do not provide methods of simultaneous estimation of the newly developed and marketed formulations. Most of the methods are available after separation of active components, which become tedious, time consuming, and lack of accuracy. Therefore, the attention in the present project was focused on to foster simple easy economical reproducible analytical method for the assessment of Aspirin and Clopidrogelbisulphate in combinations by using HPTLC Method.
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Dighade et al. (2024) studied this question.
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