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The combination of ventricular septal defect and pulmonary stenosis with a left-to-right shunt is well recognized These cases differ from the tetralogy of Fallot in that they are acyanotic, there is no dextroposition of the aorta, and the pulmonary blood flow is increased. Ventricular septal defect may also be associated with aortic regurgitation. The earliest reference to this association which we have been able to trace is that of However, to the best of our knowledge the combination of ventricular septal defect, pulmonary stenosis and aortic regurgi- tation with a left-to-right shunt has not been described. We wish to report three patients in whom we believe this combination of congenital cardiac defects exists.
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Collins et al. (1958) studied this question.
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