Inactivation of Glutamate Racemase ofPediococcus pentosaceuswith L -SerineO-Sulfate

Glutamate racemase of Pediococcus pentosaceus catalyzes the α,β-elimination of L-serine O-sulfate to produce a pyruvate concomitantly with an irreversible inactivation of the enzyme. α,β-Elimination and inactivation reactions proceed through a common intermediate. L-Serine O-sulfate serves as a suicide substrate of the enzyme.