RESERPINE has been shown to increase the production of hydrochloric acid in both man and animals.1 , 2 That reserpine is a potent stimulus to gastrointestinal secretions and motility has been clearly demonstrated by Haverback et al.,3 who observed this phenomenon after administering a dose of 1 to 3 mg. intravenously. The route of administration is not critical, since the same hypersecretory response has been observed repeatedly after the oral administration of 2 or 3 mg. daily.4 Reserpine in doses of 0.1 to 0.5 mg. daily has been found to have a tranquilizing effect and to act synergistically with hypotensive drugs.5 Because . . .
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Liebowitz et al. (1957) studied this question.
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