Key result
Transrectal ultrasonography detected biopsy-proved recurrent prostate cancer in 95% of cases, compared to 45% with digital rectal examination.
Why the study?
Does transrectal ultrasonography combined with PSA improve the detection of recurrent cancer in the prostatic fossa compared to digital rectal examination in patients following radical prostatectomy?
Population
43 patients with persistently elevated PSA levels and negative bone scintigraphy following radical…
Comparison
Transrectal ultrasonography guided biopsy… vs Digital rectal examination (DRE) combined with PSA
Design
Cohort
Authors
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Supports higher detection of recurrence by transrectal ultrasonography; leaves open whether PSA combination changes post-prostatectomy management.
Observational (n=43)
Does transrectal ultrasonography combined with PSA improve the detection of recurrent cancer in the prostatic fossa compared to digital rectal examination in patients following radical prostatectomy?
Absolute Event Rate: 95% vs 45%
The combination of PSA and transrectal ultrasonography is more effective than digital rectal examination and PSA for detecting biopsy-proven cancer recurrence following radical prostatectomy.
Foster et al. (1993) conducted an observational in Recurrent prostate cancer (n=43). Transrectal ultrasonography vs. Digital rectal examination was evaluated on Detection of biopsy-proved recurrent cancer. Transrectal ultrasonography detected biopsy-proved recurrent prostate cancer in 95% of cases, compared to 45% with digital rectal examination.
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