All present and accounted for? Cell mass spectrometry was used to determine the quantity of both gold and polystyrene nano-/microparticles taken up into cells (see picture). The uptake amounts measured for gold nanoparticles were similar to those determined by inductively coupled plasma mass spectrometry, a technique which can not be used to measure the cellular uptake of nonmetal particles.
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Lin et al. (2010) studied this question.
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