Key result
Catheter ablation of atrial fibrillation is an effective treatment modality that is superior to antiarrhythmic drug therapy for maintaining sinus rhythm, particularly in patients with paroxysmal AF.
Why the study?
Does catheter ablation improve maintenance of sinus rhythm compared to antiarrhythmic drug therapy in patients with atrial fibrillation?
Does catheter ablation improve maintenance of sinus rhythm compared to antiarrhythmic drug therapy in patients with atrial fibrillation?
This review highlights the established efficacy of catheter ablation for paroxysmal AF in middle-aged patients while noting the need for further data in elderly, heart failure, and long-standing persistent AF populations.
Supports ablation over drugs for paroxysmal AF rhythm control; leaves open optimal use in elderly, HF, and persistent AF.
Catheter ablation of atrial fibrillation (AF) is an important treatment modality for patients with AF. Although the superiority of catheter ablation of AF over antiarrhythmic drug therapy has been demonstrated in middle aged patients with paroxysmal AF, the role of catheter ablation in other patient subgroups, particularly in the elderly, those with heart failure, and those with long standing persistent AF has not been as well defined. Furthermore, although AF ablation can be performed with reasonable efficacy and safety in experienced hands, late recurrences of AF a year or more following AF ablation are not uncommon. Fortunately the techniques and tools used for AF ablation continue to evolve and it is likely that the outcomes of AF ablation will improve further in the future.
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Dewire et al. (2013) conducted a review in Atrial Fibrillation. Catheter ablation vs. Antiarrhythmic drug therapy was evaluated. Catheter ablation of atrial fibrillation is an effective treatment modality that is superior to antiarrhythmic drug therapy for maintaining sinus rhythm, particularly in patients with paroxysmal AF.
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