Key result
In nonagenarians undergoing operative interventions, ACS and P-POSSUM risk calculators significantly underestimated the need for rehabilitation and overestimated mortality (P<0.0001).
Why the study?
An aging population presents perioperative challenges, requiring evaluation of common risk calculators used for medical decision making in nonagenarian patients undergoing operative interventions.
Do common risk calculators accurately predict mortality and morbidity in nonagenarians undergoing operative interventions?
Observational
No
Do common risk calculators accurately predict mortality and morbidity in nonagenarians undergoing operative interventions?
p-value: p=<0.0001
Common surgical risk calculators may overestimate mortality and underestimate rehabilitation needs in nonagenarians, highlighting the need for specialized perioperative assessment in this extreme geriatric population.
May misestimate mortality and rehab needs in nonagenarians; leaves open the reliability of standard calculators and warrants age-specific validation.
OBJECTIVE: The nation's aging population presents novel perioperative challenges. Potential benefits of operative interventions must be scrutinized in relation to recoverable quality of life. The purpose of this study is to evaluate common risk calculators used for medical decision making in a nonagenarian patient population. METHODS: Retrospective medical record review was performed on patients 90 years or older who underwent operative interventions requiring anesthesia at a large academic medical center between January 1, 2013, and December 31, 2017. GraphPad 8.2.1 was used for statistical analysis. RESULTS: Significant differences were found when data were stratified by age for elective versus emergent cases (P value < .0001), ability to return to baseline function (P value = .0062), and mortality (P value < .0001). Significant differences were found in emergent and elective cases, ability to return to baseline function, readmissions, and mortality (all P values < .0001) when stratified by American Society of Anesthesiologists score. Ability of patients to return to baseline functionality after intervention was influenced by their preintervention level of functionality (P value = .0008). American College of Surgeons and Portsmouth Physiologic and Operative Severity Score for Enumeration of Mortality and Morbidity risk calculators underestimated the need for rehabilitation and overestimated mortality for this population (all P values < .0001). CONCLUSION: Perioperative cares of the extreme geriatric population are complex and should be approached collaboratively. Rehabilitation and postoperative assistance resources should be assessed and used fully. Input from palliative care teams should be sought appropriately. End-of-life and escalation-of-care discussions should ideally be organized prior to emergent interventions. Frailty and risk calculators should be used and considered for formal implementation into the preoperative workflow.
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Tecos et al. (2020) conducted an observational in Operative interventions requiring anesthesia in nonagenarians. Operative interventions requiring anesthesia was evaluated on Need for rehabilitation and mortality compared to ACS and P-POSSUM risk calculator predictions (p=<0.0001). In nonagenarians undergoing operative interventions, ACS and P-POSSUM risk calculators significantly underestimated the need for rehabilitation and overestimated mortality (P<0.0001).
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